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= Welcome to the Wiki Resource for TrialTree =
= Welcome to the Wiki Resource for TrialTree =
'''TrialTree''' is an innovative online platform designed to simplify the process of designing, learning about, and managing clinical trials. It combines interactive tools, educational resources, and collaborative features to make trial design more accessible for everyone—from students and early-career researchers to experienced clinicians and investigators.


== What Is TrialTree? ==
== What Is TrialTree? ==
[[File:5.png|thumb|left|75px|The TrialTree logo]]'''TrialTree''' is an innovative online platform designed to simplify the process of designing, learning about, and managing clinical trials. It combines interactive tools, educational resources, and collaborative features to make trial design more accessible for everyone—from students and early-career researchers to experienced clinicians and investigators.It offers a user-friendly, visual approach to trial design, making it accessible to researchers, clinicians, and students, even those with limited experience in clinical trial methodology. '''TrialTree''' helps users build scientifically rigorous and ethically sound clinical trials through step-by-step guidance, real-world examples, and collaborative tools.


[[File:5.png|thumb|center|300px|The TrialTree logo]]
'''TrialTree''' is a resource for anyone interested in improving the quality, ethics, and accessibility of clinical trials. Whether you're learning, designing, or teaching—'''TrialTree''' supports you every step of the way.
 
'''TrialTree''' is an innovative online platform designed to simplify the process of designing, learning about, and managing clinical trials. It offers a user-friendly, visual approach to trial design, making it accessible to researchers, clinicians, and students, even those with limited experience in clinical trial methodology.
 
TrialTree helps users build scientifically rigorous and ethically sound clinical trials through step-by-step guidance, real-world examples, and collaborative tools.
 
== 🔑 Key Features ==
 
=== 1. Interactive Trial Design ===
* Create, customize, and visualize trial protocols step by step.
* Guided decisions on:
** Randomization methods
** Blinding
** Sample size calculation
** Outcome selection
* Supports various trial types:
** Parallel
** Crossover
** Factorial
** Cluster
** Stepped-wedge
 
=== 2. Educational Tool ===
* Learn clinical trial principles in a hands-on way.
* Access examples and templates for common and complex trial designs.
* Ideal for students, trainees, and early-career researchers.
 
=== 3. Collaboration and Sharing ===
* Share trial designs with collaborators in real time.
* Export and distribute protocols for feedback and discussion.
* Foster teamwork in research environments.
 
=== 4. Focus on Equity and Inclusion ===
* Tools and guidance for designing equity-relevant trials.
* Support for incorporating:
** Diversity in participant recruitment
** Culturally responsive interventions
** Inclusive outcome measures
 
=== 5. Real-World Application ===
* Build trial protocols suitable for ethical approval and real implementation.
* Supports research across a range of disciplines including:
** HIV prevention and care
** Chronic disease management
** Global health and public health trials
 
== 🌟 Why TrialTree Is Unique ==
 
* Simplifies trial design for non-experts without sacrificing scientific rigor.
* Offers advanced features for experienced trialists.
* Bridges the gap between learning about trials and conducting them.
* Promotes equity and inclusivity in all stages of trial development.
 
== 📚 Get Started ==
* [[Types of Trials]]
* [[Formulating a Research Question]]
* [[Equipoise in RCTs]]
* [[Hypotheses in Clinical Trials]]
* [[Systematic Reviews Before RCTs]]
* [[Statistical Analysis Plans (SAPs)]]
 
== 💬 Join the Community ==
TrialTree is continuously growing and evolving. Collaborate, share your work, and help others design better trials.
 
----
 
''TrialTree is a resource for anyone interested in improving the quality, ethics, and accessibility of clinical trials. Whether you're learning, designing, or teaching—TrialTree supports you every step of the way.''
 
 
 
 
 
 
 
 
<strong>MediaWiki has been installed.</strong>
 
Consult the [https://www.mediawiki.org/wiki/Special:MyLanguage/Help:Contents User's Guide] for information on using the wiki software.


== Getting started ==
==Table of Contents==
* [https://www.mediawiki.org/wiki/Special:MyLanguage/Manual:Configuration_settings Configuration settings list]
* [https://www.mediawiki.org/wiki/Special:MyLanguage/Manual:FAQ MediaWiki FAQ]
* [https://lists.wikimedia.org/postorius/lists/mediawiki-announce.lists.wikimedia.org/ MediaWiki release mailing list]
* [https://www.mediawiki.org/wiki/Special:MyLanguage/Localisation#Translation_resources Localise MediaWiki for your language]
* [https://www.mediawiki.org/wiki/Special:MyLanguage/Manual:Combating_spam Learn how to combat spam on your wiki]


== Link To Test Page ==
{| class="wikitable" style="width:250px; background:#f9f9f9; border:1px solid #ccc; font-size:90%;"
[[My Test Page]]
|-
! colspan="1" style="background:#336699; color:white; text-align:center;" | '''TrialTree Wiki Table of Contents'''
|-
| <div class="mw-collapsible mw-collapsed">
'''Trial Foundations'''
<div class="mw-collapsible-content">
* [[Research question]] 
* [[Hypothesis]] 
* [[Equipoise]] 
* [[Systematic review]] 
* [[Types of trials]] 
* [[SPIRIT]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Trial Design Types'''
<div class="mw-collapsible-content">
* [[Cluster randomized trials]] 
* [[Cross-over trials]] 
* [[Stepped wedge trials]] 
* [[Factorial trials]] 
* [[Pragmatic trials]] 
* [[Pilot and feasibility trials]] 
* [[Vanguard trials]] 
* [[Multi-arm trials]] 
* [[Multi-arm multi-stage trials]] 
* [[Platform trials]] 
* [[Non-inferiority trials]] 
* [[N-of-1 trials]] 
* [[Expertise-based trials]]
* [[Phases of trials]]
* [[Group sequential trials]]
* [[Implementation trials]]
* [[Hybrid trials]]
* [[Registry-based trials]]
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Oversight & Participants'''
<div class="mw-collapsible-content">
* [[Data Safety and Monitoring Board]] 
* [[Trial participants]]
* [[Trial interventions]] 
* [[Trial controls]] 
* [[Trial outcomes]] 
* [[TIDieR]] 
* [[Patient and public involvement]] 
* [[Equity-relevant trials]]
* [[Quality of life measures]]
* [[Patient-reported outcomes]]
* [[Ethics]]
* [[Informed consent]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Randomization'''
<div class="mw-collapsible-content">
* [[Randomization]] 
* [[Implementing randomization]] 
* [[Allocation concealment]] 
* [[Implementing allocation concealment]] 
* [[Minimization]] 
* [[Stratification]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Blinding & Bias'''
<div class="mw-collapsible-content">
* [[Blinding]] 
* [[Implementing blinding]] 
* [[Preventing attrition]]
* [[Internal and external validity]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Analysis & Interpretation'''
<div class="mw-collapsible-content">
* [[Statistical Analysis Plan (SAP)]] 
* [[Sample size]] 
* [[Analysis]] 
* [[Intention-to-treat analysis]] 
* [[Per-protocol analysis]] 
* [[Subgroup analysis]] 
* [[Sensitivity analysis]] 
* [[Multiple testing]] 
* [[Clinical versus statistical significance]]
* [[Frequentist and Bayesian approaches]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Cost & Scalability'''
<div class="mw-collapsible-content">
* [[Cost effectiveness]] 
* [[Scaling up]] 
* [[Budgeting]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Data & Documentation'''
<div class="mw-collapsible-content">
* [[Database creation]] 
* [[Data management plan (DMP)]] 
* [[Missing data]]
* [[Digital tools]] 
</div>
</div>
|-
| <div class="mw-collapsible mw-collapsed">
'''Reporting Guidelines'''
<div class="mw-collapsible-content">
* [[CONSORT]] 
* [[SPIRIT]] 
</div>
</div>
|}

Latest revision as of 17:03, 28 June 2025

Welcome to the Wiki Resource for TrialTree

What Is TrialTree?

The TrialTree logo

TrialTree is an innovative online platform designed to simplify the process of designing, learning about, and managing clinical trials. It combines interactive tools, educational resources, and collaborative features to make trial design more accessible for everyone—from students and early-career researchers to experienced clinicians and investigators.It offers a user-friendly, visual approach to trial design, making it accessible to researchers, clinicians, and students, even those with limited experience in clinical trial methodology. TrialTree helps users build scientifically rigorous and ethically sound clinical trials through step-by-step guidance, real-world examples, and collaborative tools.

TrialTree is a resource for anyone interested in improving the quality, ethics, and accessibility of clinical trials. Whether you're learning, designing, or teaching—TrialTree supports you every step of the way.

Table of Contents

TrialTree Wiki Table of Contents

Trial Foundations

Trial Design Types

Oversight & Participants

Randomization

Blinding & Bias

Analysis & Interpretation

Cost & Scalability

Data & Documentation

Reporting Guidelines

Retrieved from "https://wiki.trialtree.site/index.php?title=Main_Page&oldid=306"