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''TrialTree is a resource for anyone interested in improving the quality, ethics, and accessibility of clinical trials. Whether you're learning, designing, or teaching—TrialTree supports you every step of the way.'' | ''TrialTree is a resource for anyone interested in improving the quality, ethics, and accessibility of clinical trials. Whether you're learning, designing, or teaching—TrialTree supports you every step of the way.'' | ||
==Table of Contents== | ==Table of Contents== | ||
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! colspan="1" style="background:#336699; color:white; text-align:center;" | '''TrialTree Wiki Table of Contents''' | ! colspan="1" style="background:#336699; color:white; text-align:center;" | '''TrialTree Wiki Table of Contents''' | ||
|- | |- | ||
| '''Trial Foundations''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Research Question]] | '''Trial Foundations''' | ||
* [[Hypothesis]] | <div class="mw-collapsible-content"> | ||
* [[Equipoise]] | * [[Research Question]] | ||
* [[Systematic Review]] | * [[Hypothesis]] | ||
* [[Types of trials]] | * [[Equipoise]] | ||
* [[SPIRIT]] | * [[Systematic Review]] | ||
* [[Types of trials]] | |||
* [[SPIRIT]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Trial Design Types''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Cluster randomized trials]] | '''Trial Design Types''' | ||
* [[Cross-Over Trials]] | <div class="mw-collapsible-content"> | ||
* [[Stepped wedge trials]] | * [[Cluster randomized trials]] | ||
* [[Factorial Trials]] | * [[Cross-Over Trials]] | ||
* [[Pragmatic trials]] | * [[Stepped wedge trials]] | ||
* [[Pilot and feasibility trials]] | * [[Factorial Trials]] | ||
* [[Vanguard Trials]] | * [[Pragmatic trials]] | ||
* [[Multi-Arm Trials]] | * [[Pilot and feasibility trials]] | ||
* [[MAMS]] | * [[Vanguard Trials]] | ||
* [[Platform Trials]] | * [[Multi-Arm Trials]] | ||
* [[Non-Inferiority Trials]] | * [[MAMS]] | ||
* [[N-of-1 trials]] | * [[Platform Trials]] | ||
* [[Expertise-Based Trials]] | * [[Non-Inferiority Trials]] | ||
* [[N-of-1 trials]] | |||
* [[Expertise-Based Trials]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Oversight & Participants''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Data Safety and Monitoring Board]] | '''Oversight & Participants''' | ||
* [[Trial Participants]] | <div class="mw-collapsible-content"> | ||
* [[Trial Interventions]] | * [[Data Safety and Monitoring Board]] | ||
* [[Trial Controls]] | * [[Trial Participants]] | ||
* [[Trial Outcomes]] | * [[Trial Interventions]] | ||
* [[TiDier]] | * [[Trial Controls]] | ||
* [[Patient and Public Involvement]] | * [[Trial Outcomes]] | ||
* [[Equity-relevant trials]] | * [[TiDier]] | ||
* [[Patient and Public Involvement]] | |||
* [[Equity-relevant trials]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Randomization''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Randomization]] | '''Randomization''' | ||
* [[Implementing randomization]] | <div class="mw-collapsible-content"> | ||
* [[Allocation concealment]] | * [[Randomization]] | ||
* [[Implementing allocation concealment]] | * [[Implementing randomization]] | ||
* [[Minimization]] | * [[Allocation concealment]] | ||
* [[Stratification]] | * [[Implementing allocation concealment]] | ||
* [[Minimization]] | |||
* [[Stratification]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Blinding & Bias''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Blinding]] | '''Blinding & Bias''' | ||
* [[Implementing blinding]] | <div class="mw-collapsible-content"> | ||
* [[Preventing Attrition]] | * [[Blinding]] | ||
* [[Implementing blinding]] | |||
* [[Preventing Attrition]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Analysis & Interpretation''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Statistical Analysis Plan (SAP)]] | '''Analysis & Interpretation''' | ||
* [[Sample Size]] | <div class="mw-collapsible-content"> | ||
* [[Analysis of Trials]] | * [[Statistical Analysis Plan (SAP)]] | ||
* [[Intention-to-Treat (ITT) Analysis]] | * [[Sample Size]] | ||
* [[Per-Protocol (PP) Analysis]] | * [[Analysis of Trials]] | ||
* [[Subgroup Analysis]] | * [[Intention-to-Treat (ITT) Analysis]] | ||
* [[Sensitivity Analyses]] | * [[Per-Protocol (PP) Analysis]] | ||
* [[Multiple Testing]] | * [[Subgroup Analysis]] | ||
* [[Statistical vs. Clinical Significance]] | * [[Sensitivity Analyses]] | ||
* [[Multiple Testing]] | |||
* [[Statistical vs. Clinical Significance]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Cost & Scalability''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Cost effectiveness]] | '''Cost & Scalability''' | ||
* [[Scaling up]] | <div class="mw-collapsible-content"> | ||
* [[Budgeting]] | * [[Cost effectiveness]] | ||
* [[Scaling up]] | |||
* [[Budgeting]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Data & Documentation''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[Database Creation]] | '''Data & Documentation''' | ||
* [[Data Management Plans (DMP)]] | <div class="mw-collapsible-content"> | ||
* [[Missing Data]] | * [[Database Creation]] | ||
* [[Data Management Plans (DMP)]] | |||
* [[Missing Data]] | |||
</div> | |||
</div> | |||
|- | |- | ||
| '''Reporting Guidelines''' | | <div class="mw-collapsible mw-collapsed"> | ||
* [[CONSORT]] | '''Reporting Guidelines''' | ||
* [[SPIRIT]] | <div class="mw-collapsible-content"> | ||
* [[CONSORT]] | |||
* [[SPIRIT]] | |||
</div> | |||
</div> | |||
|} | |} | ||
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== 💬 Join the Community == | == 💬 Join the Community == | ||
TrialTree is continuously growing and evolving. Collaborate, share your work, and help others design better trials. | TrialTree is continuously growing and evolving. Collaborate, share your work, and help others design better trials. | ||
Revision as of 05:00, 26 March 2025
Welcome to the Wiki Resource for TrialTree
TrialTree is an innovative online platform designed to simplify the process of designing, learning about, and managing clinical trials. It combines interactive tools, educational resources, and collaborative features to make trial design more accessible for everyone—from students and early-career researchers to experienced clinicians and investigators.
What Is TrialTree?
TrialTree is an innovative online platform designed to simplify the process of designing, learning about, and managing clinical trials. It offers a user-friendly, visual approach to trial design, making it accessible to researchers, clinicians, and students, even those with limited experience in clinical trial methodology.
TrialTree helps users build scientifically rigorous and ethically sound clinical trials through step-by-step guidance, real-world examples, and collaborative tools.
TrialTree is a resource for anyone interested in improving the quality, ethics, and accessibility of clinical trials. Whether you're learning, designing, or teaching—TrialTree supports you every step of the way.
Table of Contents
| TrialTree Wiki Table of Contents |
|---|
Trial Foundations |
Blinding & Bias |
Cost & Scalability |
Data & Documentation |
💬 Join the Community
TrialTree is continuously growing and evolving. Collaborate, share your work, and help others design better trials.