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• 19:46, 26 March 2025 Lawrence talk contribs created page Group sequential trials (Created page with "= Group sequential trials = A '''Group Sequential Trial''' is an adaptive randomized controlled trial (RCT) design that incorporates pre-planned interim analyses at defined time points before the trial concludes. This approach enables researchers to stop the trial early for efficacy, futility, or safety concerns. By doing so, group sequential designs can conserve resources, minimize participant exposure to ineffective treatments, and accelerate regulatory decision-makin...")